Brandon Sesay (born December 16, 1986) is an American football defensive lineman who is a free agent.

He played college football at the Texas Tech University and attended Douglass High School in Atlanta, Georgia.

He has been a member of the Iowa Barnstormers, West Texas Roughnecks, San Antonio Talons, Tampa Bay Storm, Portland Steel, Washington Valor, Albany Empire (AFL) and Albany Empire (NAL).

Sources: In November 2004, Sesay committed to play football for the Georgia Bulldogs.

On September 9, 2021, Sesay signed with the Albany Empire of the National Arena League (NAL).