The former Brandreth Pill Factory is a historic industrial complex located on Water Street in Ossining, New York, United States.

[3] Benjamin Brandreth made his family's popular medicine, said to treat blood impurities, at the factory, starting in the 1830s.

The land is level due to the proximity of the river; Water Street generally follows the lower edge of a steep wooded bluff to the north end of the site, where a stream flows into the Hudson and opens a wide gorge.

Just past the fork to Solitude Lane, about 400 feet (120 m) north of the intersection with Snowden Avenue and Westerly Road, are the first set of buildings.

Doric pilasters at each corner, along with three at evenly spaced intervals along between windows along the north and south facades, support a blank entablature below the roof.

[2] Another 150 feet (46 m) to the north, also between the road and the tracks, is a corrugated iron storage facility built on the original factory site.

Fenestration consists of rectangular windows with granite sills and lintels along the north and south profiles, with an oculus in the gable apex.

Stone steps lead to the paneled wooden and glass doors, sheltered by a curved canopy supported by large brackets at the sides.

Inside the remaining original features include intricately molded woodwork and ceiling medallions, door hardware and a vault with a stone floor and brick walls.

He pioneered the use of advertising with testimonials to the effectiveness of the pills' treatment of the blood impurities thought to create disease at the time, and developed a growing presence in the English and American markets.

It may have been designed by Calvin Pollard, who built two houses in Ossining for Brandreth (neither extant) during this period as well as St. Paul's Episcopal Church downtown.

In 1848, he purchased an interest in fellow English American Thomas Allcock's Porous Plasters and began developing a facility to manufacture them on an old mill site further up the river.

[3] The pills were well known enough that Herman Melville mentioned them in Moby-Dick and Edgar Allan Poe devoted part of his story "Some Words with a Mummy" to a fanciful discussion of what their ingredients might be.

Back in Ossining, Brandreth helped establish two banks, and was on the founding board of Dale Cemetery, still the community's largest.

During the later years of the 19th century and the early 20th, the factory began to diversify its operations in response to increasing federal regulation of the patent-medicine industry.

The company was making nail polish, mannequins, cell forms for bulletproof fuel tanks and the Havahart line of non-lethal animal traps.

[2] In 1940 the company sold the buildings at the southern end of the property to the Gallowhur corporation, which used them to make insect repellent and suntan lotion.

In the 2000s a local developer, Plateau Associates, proposed the Hidden Cove on the Hudson project for the main building area.

Plateau hoped to obtain Leadership in Energy and Environmental Design (LEED) certification for the completed units.

In 2011 it prepared to submit a final EIS, with Hidden Cove now, in the wake of the Great Recession, changed to luxury rental units.

[4] However, in 2007, the Federal Emergency Management Agency (FEMA) had issued updated flood plain maps for the Hudson River.

[4] Before Sandy, the already-deteriorated building's ground floor would have to be raised at least two feet, making it impossible to put any residential units on it.