Brazil sent a delegation to compete at the 2008 Summer Paralympics in Beijing, China The country debuted in the Games in 1972 and 2008 was its 10th participation.

Brazil did not include any competitors in the archery and wheelchair rugby.

In the Opening Ceremony, the Brazilian Flag bearer was the judoka Antônio Tenório Silva, who became four-time Paralympic champion in his category.

In 2008, Brazil had its second strongest showing in the history of the Games, finishing in respectable 9th place.

André Brasil and Daniel Dias, both of swimming and Lucas Prado of athletics were Brazil's top medalists.