[1] Students participate in a various activities, including faith and service-related clubs, music and drama productions, and athletic programs at both the intramural and extramural levels.

The school began offering an application-based STEAM (Science, Technology, Engineering, Arts, and Mathematics) program in 2020.

In 1649 an Iroquois raid on a Huron village captured de Brébeuf, aged 56, and others; they were ritually tortured and killed.

Immediately, Cardinal Gerald Emmett Carter and the staff of the Archdiocese of Toronto began to explore the possibilities to ensure the continual operation of Brebeuf.

In February 1984, Cardinal Carter's office announced that the Presentation Brothers were willing to assume responsibility for Brebeuf College, and would officially take over on July 31, 1984.

The Presentation Brothers of Mary are a religious congregation founded with a single intention—to work for the Christian education and the formation of youth.

After entering a monastery in Europe, he realized that his real vocation lay with the uneducated and poverty-stricken youth of Waterford.

Today the Presentation Brothers operate elementary and secondary schools in the West Indies, Ireland, Ghana, Nigeria, and Canada.

In 2001, the Toronto Catholic District School Board announced funding for a new building to replace Brebeuf's outdated facilities and invested Can$23 million.

Under Principal Michael Pautler '76, the Brebeuf community was temporarily housed in the former Bathurst Heights Secondary School (later John Polanyi Collegiate Institute) while the new building was being constructed.

On January 5, 2004, exactly forty years after Bishop Pocock presided over Brebeuf College School's Solemn Blessing, staff and students began classes in the new facility at the old campus.

The Latin motto "Studio Gradum Faciant" is translated "To win merit through study", emphasizing the academic nature of the school.

Students are encouraged to put their faith into action as "men for others" in various charity drives and social justice initiatives.

[5][6][7][8][9] In 2011 the school instituted the first of its international service and leadership programmes with a trip to Ghana in conjunction with the Presentation Brothers.

Students who achieve Honour Roll status for every year of high school are inducted into the Blessed Edmund Rice Society, named for the Founder of the Presentation Brothers, at Graduation.

There are awards for the highest overall average in each grade and these are named for the college's Jesuit principals: In 2012, the school created the Order of St Jean de Brebeuf to recognize members of the school community who exemplify the values and ideals for which Brebeuf College School stands, namely: faith, discipline, integrity, hard work, humility, excellence, success, pursuit of the greater good, friendship, and community, and for always being 'Men and Women For Others'.

In addition to on-campus co-curricular activities, the school's chaplaincy department also offers various annual excursions for students ranging from three-day overnight retreats to eleven-day pilgrimages to Italy during Holy Week.

It broadcasts announcements, weather, the house competition leaderboard, video clips produced by the school's media arts and communications technology courses.