She signed to EMI Records (former) in 2018 and subsequently released her first commercial EP Be Runway (2019), followed by her debut mixtape, 2000and4Eva (2020), which spawned the single "ATM" featuring Missy Elliott.
[7] At the age of 9, Runway experienced bullying and colourism which caused her to bleach her skin and have a negative chemical reaction to the product.
Runway discussed that she purchased a "DIY home studio" setup with her first pay cheque which was where she was singing over self-produced beats and writing her own songs.
Earlier material such as RNWY 01 was recorded with her DIY setup and explained that the self-sufficiency taught her what musical sound she wanted to pursue.
[8] Bree Runway made her solo debut with the self-released EPs titled RNWY 01 and Bouji being released in November 2015 and May 2016 respectively.
A music video was released alongside the song, which was shot in Dubai, by model Leomie Anderson and directed by Runway herself.
[13] The video would gather major attention, being her first to pass over one hundred thousand views, and praise due to its serious message of exploitation of young females in the fashion industry.
[14] Bree Runway was featured on British electronic duo Metroplane's single "Word of Mouth" which was released in February 2018.
On 5 March 2020, Bree Runway released the single "Apeshit" which was met with critical acclaim and drew immediate comparisons to Missy Elliott who would later co-sign the track on Twitter.
[23] On 28 April 2020, Runway announced that her next single would be titled "Damn Daniel" and would be a collaboration with American singer and rapper Baby Tate.
[25] The song was featured on Annie Mac's Future Sounds show on BBC Radio 1 as the "Hottest Record in the World" on 30 April.
[41] By July, Runway announced she had parted ways with EMI & Universal and that she would continue to release music as an independent artist.
[45] She cites Foxy Brown,[46] Lil' Kim, Britney Spears, Madonna, Missy Elliott, Pharrell, Kelis and the Neptunes as her biggest influences.