Brenda Tiggausina Itta (born November 13, 1943)[1] is an Iñupiaq activist and former legislator in Alaska's House of Representatives.

"[4] In 1966, at age 22, she moved to Washington, D.C. to work as a receptionist to Senator Ernest Gruening, where she quickly became known as "that Eskimo girl.

[4] During this time, Itta worked with many Iñupiat leaders and became heavily involved with land claim settlements and Native affairs in Alaska, spurred on by the interactions she had with people while serving as Senator Gruening's aide.

She served as a Coordinator for the Post Secondary Education Program in the North Slope Borough School District.

[8][1] Itta has continued her engagement with the Native American community, sharing her knowledge through institutions like the Eileen Panigeo MacLean House at the University of Alaska Fairbanks.