Brenda L. Murphy (born 1958 or 1959) is a Canadian activist and politician who served as the 32nd lieutenant governor of New Brunswick, from 2019 to 2025.

[3] She formerly served as a municipal councillor in Grand Bay–Westfield and served as the executive director of the Saint John Women's Empowerment Network in Saint John, best known for her advocacy on poverty and domestic violence issues.

[1] In April 2022, the Court of Queen's Bench of New Brunswick ruled that her appointment as lieutenant governor violated the bilingual status of the province under the Charter of Rights and Freedoms, since Murphy is unilingual English-speaking.

[6] On November 15, 2024, Louise Imbeault was announced as Murphy's replacement.

Her partner Linda Boyle has accompanied her on official engagements, including a visit to King Charles III at Buckingham Palace in November 2022.