Brendan Bayliss (born August 11, 1976) is an American musician and the founder, a lead guitarist, and primary vocalist for progressive rock band Umphrey's McGee.

Bayliss attended St. Joseph's High School (South Bend, Indiana) and went on to attend the University of Notre Dame, where his father Bob Bayliss was the men's tennis coach,[2] and formed the Star Wars inspired Tashi Station with bass player Ryan Stasik and keyboardist Gregg Andrulis.

After the band split in the fall of 1997, Bayliss and Stasik joined up with Joel Cummins and Mike Mirro – two former members of another recently defunct local band, Stomper Bob – to form Umphrey's McGee.

Bayliss uses Paul Reed Smith guitars, Mesa/Boogie and Oldfield amps, endorses VOX Classic Plus amps, and along with the rest of Umphrey's McGee endorses Morley pedals and BBE Sound equipment.

Bayliss and fellow musician Jeff Austin formerly of Yonder Mountain String Band played a handful of shows together starting the summer of 2006 and, as of May 11, 2010, had released a studio album together under the name 30db.