His father, Francis (Frank), is an Irish immigrant who came to the United States in 1970 from Glencolmcille, a district of County Donegal, and works as a janitor for the Southeastern Pennsylvania Transportation Authority (SEPTA).

His late mother, Eileen, was the child of Irish immigrants from County Sligo; she worked as a Philadelphia School District crossing guard for over 20 years.

He attended Cardinal Dougherty High School before receiving an academic scholarship to the University of Notre Dame, where he earned a Bachelor of Arts degree in 1999, completing the Hesburgh Program in Public Service.

[8] Boyle ran unopposed again in 2014 resigned his seat on January 2, 2015, before being sworn in as a member of the United States House of Representatives.

During his first term in office, he introduced the REACH Scholarship program, which would offer tuition-free public college for qualifying Pennsylvania students.

[10][11][12] In April 2013, Boyle announced his candidacy for Pennsylvania's 13th congressional district, which stretched from Montgomery County to northeast Philadelphia.

[6] Boyle ran against former Congresswoman Marjorie Margolies, then state Senator Daylin Leach and current Montgomery County Commissioner Valerie Arkoosh for the Democratic nomination.

[24] As a member of Congress, Boyle has prioritized legislative measures to address national income inequality, while expanding access to healthcare and education.

He has supported legislation to raise the federal hourly minimum wage to $12 and measures to revise the way Social Security benefits are calculated to keep them from being reduced over time.

[29][30] Boyle and other members of Congress' Philadelphia delegation sought federal funding to remove asbestos, mold, lead paint, and other environmental toxins from schools.

[35] He joined the majority of House Democrats in opposing the Laken Riley Act, a bill to require immigration authorities to detain migrants suspected of burglary and theft.

It will ensure that Ukraine has the support it needs to fight back against Vladimir Putin, and that Israel can continue to defend itself against Hamas while delivering vital humanitarian assistance to civilians in Gaza.

"[45] On July 20, 2024, Boyle called on U.S. Secret Service Director Kimberly Cheatle to resign in the wake of an assassination attempt against former President Trump, making him the first Congressional Democrat to do so.

[46] In November 2024, Boyle praised the possible return of Robert Lighthizer as United States Trade Representative, who served as Donald Trump's appointee during his first presidential term.

[64] In 2011, the Aspen Institute chose Boyle as one of its Rodel Fellows,[65] a program that "seeks to enhance our democracy by identifying and bringing together the nation's most promising young political leaders.