Brendon Dedekind (born 14 February 1976 in Pietermaritzburg, KwaZulu-Natal) is a South African retired swimmer.

He won an international championship gold medal in the 50 m freestyle at the 1999 Pan Pacific Swimming Championships.

Nicknamed Skinny Man, he competed in two consecutive Summer Olympics for his native country, starting in 1996, when he was a finalist in the 50 m freestyle.

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