[citation needed] Spence chaired the U.S. House Banking and Currency Committee (1943–1963, except for four years when Republicans controlled Congress).

This led to creating the International Monetary Fund and Bank, and Spence's sponsoring legislation in Congress.

[citation needed] The Brent Spence Bridge of I-75/I-71 which crosses the Ohio River at Covington, Kentucky is named for him.

His funeral service was at St. Paul's Episcopal Church, Newport, where he was a lifetime member,[4] then buried in Evergreen Cemetery (Southgate, Kentucky).

"Brent Spence and the Bretton Woods Legislation", The Register of the Kentucky Historical Society 79 (Winter 1981).