Brentsville District High officially opened on September 5, 1929, and hosted grades one through eleven.

Remodeling plans for 2006 included the refitting of the auditorium, adding more comfortable seats, bowing the stage, and replacing a sound panel wall.

In the 2020–2021 school year, Brentsville's student body was:[2] Brenstville District High School offers its students the opportunity to enroll in The Cambridge Programme and to take Cambridge University's international examinations both toward individual subject certificates as well as work towards and AICE certificate.

As of 2014, there are 33 student groups considered official extracurricular programs at Brentsville District High School.

For post-season purposes, Brentsville is assigned to Conference 28 as it is a Group 3A school in the eastern region.

Brentsville's official mascot for all sporting events is the tiger, the school colors are black and orange.