The Conservatoire botanique national de Brest (32 hectares) is a notable botanical garden located at 52 Allée du Bot, Brest, Finistère, in the region of Brittany, France.

The conservatory site was formerly a quarry and rubbish dump, purchased in 1971 by the municipality to create open space.

The conservatory itself was founded in 1977 with a primary mission of preserving endangered species from the Armorican Massif (including parts of Brittany, Basse-Normandie and Pays de la Loire), France, Europe, and islands around the world, but also including plants from China, Japan, the Americas, Australia, and New Zealand.

These very rare plants include Brighamia insignis, Centaurium favargeri, Cheirolophus massonianus, Cylindrocline lorencei, Dombeya cacuminum, Hibiscus insularis, Hibiscus liliiflorus, Impatiens thomassetii, Limonium humile, Normania triphylla, Ruizia cordata, and Trochetia boutoniana.

Additional specimens of interest include Amorphophallus titanum, Asparagus fallax, Astrophytum myriostigma, Angraecum sesquipedale, Commelina rupicola, Geranium maderense, Hibiscus storckii (H. rosa-sinensis), Lavandula pinnata, Limonium dendroides, Monizia edulis, Pachypodium rosulatum, Pelargonium cotyledonis, Tolpis glabrescens, Tournefortia bojeri, and Turbina inopinata.