He played in Major League Baseball for the Montreal Expos, Florida Marlins, Baltimore Orioles, and Chicago Cubs.

The Montreal Expos selected Barberie in the seventh round of the 1988 Major League Baseball (MLB) Draft.

He recorded the first hit in Marlins franchise history, a single off of Orel Hersheiser, on Opening Day.

[9] In May 1994, Barberie got chili pepper juice in his eye when putting in his contact lenses, was temporarily blinded, and missed that day's game as a result.

[16] The next season, Barberie played for the Oklahoma City RedHawks of the PCL, an affiliate of the Texas Rangers.

[3] Bret is the former husband of Jillian Barberie, a Canadian television hostess, sportscaster, radio personality and actress.