The Württemberg Western Railway and the Kraichgau line cross at the station.

Bretten station was opened on 1 October 1853 as part of the construction of Western Railway from Stuttgart to Bruchsal.

In May 1994, Stadtbahn line S9 opened from Bruchsal to Bretten and it was extended to Mühlacker in 1999.

Among other things, the platforms were raised, waiting rooms were enlarged and a toilet was built.

"Track plan of Bretten station" (PDF, 193.74 kB) (in German).