A Republican, Manktelow has represented the 130th district of the New York State Assembly, based in Wayne County along Lake Ontario, since 2019.

When he returned, Manktelow took classes at the University of Chicago and Finger Lakes Community College, but did not attain degrees from either.

[4] Manktelow ran in 2016 for New York's 54th State Senate district, vacated by retiring Republican Michael F. Nozzolio.

[5] After longtime State Assemblyman Bob Oaks announced his retirement in 2018, Manktelow launched his campaign for the 130th Assembly district.

[6] He won the primary uncontested, and defeated Democrat Scott Comegys in the general election with 67% of the vote.