Circa 1966 he "chaired an ad hoc committee under the USAF Science Advisory Board (AFSAB) looking into the UFO problem".

In 1923 he moved to J. N. Adam Memorial hospital in Perrysburg, New York, a tuberculosis sanitarium run by Buffalo's public health department.

Due to a general interest in biological effects of solar radiation, he published some of the early work on the ozone layer and erythema caused by the sun.

The carbon arcs developed at Perrysburg were an ideal source of ultraviolet, but for proper irradiation, the milk had to be in a very thin film.

... A film of high enough flow volume for commercial application was produced, and vitamin D-fortified milk became widespread.

"[10] At the time the Institute was dealing with a spike in number of students and attempted to tailor the curriculum for military usefulness.

In a report sent to President Valentine, O' Brien estimated that the Institute had "spent" about one million dollars for the war effort "including overhead allowances to the University.

"[12] In his '47 report, O'Brien pointed out the number of government and industry requests made for the Institute to conduct research.

"[13] He decided he was much more interested "guiding research and advanced degree students than in the tiresome details of undergraduate instruction.