Brian O'Shea (born 9 December 1944) is an Irish former Labour Party politician who served as Minister of State at the Department of Health from 1994 to 1997 and Minister of State at the Department of Agriculture, Food and the Marine from 1993 to 1994.
He served as a Teachta Dála (TD) for the Waterford constituency from 1989 to 2011.
O'Shea was elected to Seanad Éireann in 1987 as a Senator for the Industrial and Commercial Panel.
In 1994, he was appointed Minister of State at the Department of Health with responsibility for Mental Handicap, Public Health and Food Safety.
He was party spokesperson for Defence (1997–1998); Education; Arts, Heritage, Gaeltacht and the Islands; Communications and Sport (1998–2002); Community, Rural and Gaeltacht Affairs (2002–2007); and Defence and the Irish language (2007–2011).