Born in Aboudé, Ivory Coast, Dja Djédjé started his career with French side Evian and amassed over 100 appearances, scoring six times across four seasons.

[5] On 28 January 2014, Dja Djédjé signed a four-and-a-half-year deal with Ligue 1 club Olympique de Marseille.

[6] After sitting on the bench for some matches early in his Marseille career, Dja Djédjé quickly became a regular starter, displacing Rod Fanni as the club's first-choice right back.

In the 2014–15 season, Dja Djédjé operated as a wing back in several matches as manager Marcelo Bielsa looked for him to provide width and support for Marseille's wide attacks.

[8] On 21 July 2016, Dja Djédjé joined Premier League side Watford for £3 million on a four-year deal.