She played for the National Water Polo League's Queensland Breakers before switching to the Victorian Tigers for the 2012 season.
[4] She is 182 cm (6 ft 0 in) tall, weighs 85 kilograms (13 st 5 lb), is right-handed and has a tattoo featuring the Olympic rings.
[6] Knox attended Hartwick College in New York on a water polo scholarship,[5] and Griffith University, where she earned a Bachelor of Biomedical Science.
[15] In the 2013–14 season, Knox played for the Greek powerhouse Olympiacos in the European competitions, winning the LEN Trophy.
In 2002, she was a member of the national youth girls team that toured the United States in June, and competed in an international series in Sydney in August.
[2][19] She received her first call up to Australia's senior team to compete at the 2005 World Championships in Canada,[2][19] where she scored her first international goal in her first game, which was against Germany.
[22] In a 2008 Asia-Oceania qualifier against China for the World League Super Finals, she played in the 11–9 win that went to a penalty shoot out, scoring three of the goals for Australia.
[25] In May 2010, she was a member of the team that competed at the FINA World League Asia-Oceania zone held in Osaka, Japan, and Tianjin, China.
[28] She went on to compete in the FINA World League Finals in La Jolla, California, and Australia took home a silver medal.
Her coach was quoted in The Age about her performance in the match, saying "Bronwen Knox was excellent at centre back and the pressure allowed us to get steals and counter-attacks.
[31] In April 2011, she attended a training camp at the Australian Institute of Sport where the coach was "selecting a team for the major championships over winter.
"[33] In 2011, she was one of five Queensland women to compete for the Australian Stingers in the FINA World League competition held in Auckland, New Zealand.
[27] In July 2011, Knox was a member of the Australian Stingers that competed in the 2011 FINA World Championships in Shanghai as a field player.
[41] Knox was the Deputy Chef de Mission to help manage the Australian team on the ground at the 2024 Paris Olympics.