[2] According to Dave Cockrum, the Brood were originally conceived to serve as generic subordinates for the main villain of The Uncanny X-Men #155: "We had Deathbird in this particular story and Chris [Claremont] had written into the plot 'miscellaneous alien henchmen.'

The Brood, like most alien species, possess advanced technology, however due to their nature it's unknown if they developed it themselves or assimilated it for their own benefit.

These include: The Brood are the Main Universe's first natural predators, spawned on a dark galaxy prior to the emergence of Galactus from his incubator.

[13] In the next eight million years of experimentation, the Black Judges deemed the Brood a major success and were unleashed on the Shi'ar Galaxy where the Brood found certain large space-dwelling creatures that they decided to prey to use as living starships to infest neighboring star systems and initiating an intergalactic campaign to build a fearsome empire.

[17] Years later, Kree warrior Mar-Vell, has been ordered to make contact with the stranded Grand Admiral Devros on a planet in the Absolom Sector, a region known to be infested with Brood, Mar-Vell's team, which includes the medic Una and Colonel Yon-Rogg, was ambushed by Brood warriors after landing on the planet and taken prisoner by the Brood-infected Devros.

[15] As a reward for their help, Deathbird gives the Brood Lilandra, the X-Men, and Carol Danvers, along with Fang of the Imperial Guard, to use as hosts.

[19] Another branch of the Brood manage to land on Earth and infect more mutants, along with the Louisiana Assassins Guild of which X-Man Gambit is a member.

Unable to stop future waves of Assassins from coming, the X-Man, Iceman, freezes Connover, putting her in suspended animation and causing the current firstborn to kill themselves, as in their minds the mission was accomplished.

Fortunately, Iron Man realizes that the Brood are drugging food to amplify aggression- relying on his armor's own life-support systems to prevent him succumbing to the 'infection'- and is able to uncover the plot.

[15] Although the Queen had already absorbed the powers and skills of the various contest winners- in the form of Captain America, Thor, the Hulk, Spider-Man, Jean Grey and the Scarlet Witch-, the remaining heroes managed to defeat her.

After battling them, they left the station leaving the infected crew members alive despite the desires of Wolverine and Emma Frost to kill them due to the interference of the Invisible Woman.

Using an enhanced Cerebro, Emma Frost projected a telepathic hallucination of the Phoenix and Galactus appearing in the city, which caused the Brood to panic and recall their forces to the dozens of Acanti ships after which they fled Earth.

[22] It was also revealed that at some point in the dawn of civilization during the year 2610 BC, a spaceship filled with Brood crash landed in Egypt, marking the end of the second great dynasty.

They went as far as turning a Pharaoh into one of their own and it also would have been the end of days if not for Imhotep and a group of soldiers, among them En Sabah Nur, who were able to successfully fend off the invasion.

[23] The Brood return to Earth in the Ms. Marvel series and battle Carol Danvers, who as Binary played a key role in their earlier defeat.

Strangely enough, none of the Brood present recognize who she is, possibly because of her inability to fully access her cosmic powers, which also changed her physical appearance.

Ms. Marvel, seeing her as a threat, fought Cru again and in the process merged part of their minds temporarily making them unable to use their powers and therefore vulnerable to the Brood.

A Brood referred to as "No-Name", who becomes a genetic queen because their race is becoming rarer, becomes the lover of insect king Miek and also appears in World War Hulk.

Nicknamed "Broo" by Oya, the Broodling was a mutant, and both intelligent and non-violent able to wear clothing and glasses (which he felt made him look less frightening).

Weapon H stated that those who claim to help people will kill them anyway and has the Brood-infected human carry a message to Roxxon to leave him alone.

Her attempts at targeting astronauts were thwarted by the discovery that J. Jonah Jameson is the perfect host but Frank Castle was able to interfere.

The X-Men beat them back while Broo and his colleagues studied the egg and learn that it actually was the King Egg, a superweapon developed by Kree scientists thousands of years before the modern Marvel Universe on the Kree capital world of Hala, to foster the Brood race and instill a patriarchal element that, when activated, could give one member a supercharged version of the Empress' pheromonal control to turn the entire Brood species into a controllable army.

After crash-landing on an abandoned planet, it initially looks like the assembled heroes are going to be overwhelmed and wiped out by the sheer magnitude of Brood attacking them.

Some time later, the X-Men got a distress call from deep space and find that the galaxy’s Brood problem is not as solved as they’d thought!

When the X-Men’s close friend Broo became the Brood King, he gained the ability to control the savage alien race he was both a part of and so different from.

Summers eventually escaped, and began infecting other humans (Including the AoA version of Joseph "Robbie" Robertson, as well as friends of Misty Knight and Colleen Wing).

The Summers brothers cremated their father and indirectly deprived Sinister of the chance to carry out further tests on Brood DNA.

[66] In X-Men: The End, taking place in a possible future, the Brood hatch a plan with Lilandra (possessed by Cassandra Nova).

Nova plans to solidify her rule over Shi'ar space by smuggling an other-dimensional pure-Brood queen from an alternate universe.

[67][68][69] During the attack of insanity brought by Psiclone, the androgynous harlot Cash imagined the Brood between the races of extraterrestrials who swarmed the streets of Transverse City.