[1] Among his top horses, Isaacs owned Intent, whose wins included back-to-back editions of the San Juan Capistrano Handicap and who went on to sire Intentionally, Isaacs' 1959 American Champion Sprint Horse.
Among his other sporting interests, Isaacs served as president of the Maryland Kennel Club for 20 years and was a key figure in the introduction of the Rottweiler breed to the United States.
Listed on the National Register of Historic Places, Isaacs undertook a full restoration of the house designed in part by Benjamin Henry Latrobe whose construction began in 1811.
[2] Diagnosed with terminal cancer, Isaacs set up a non-profit foundation to which he donated the entire 400-acre property to be operated as a museum.
[3] Isaacs also established a scholarship fund to benefit the children of persons who worked for his companies and for graduates of public high schools in the city of Baltimore, Maryland.