On October 19, 2007, Ali appeared on Late Night with Conan O'Brien and performed "Take Me Home" from The Undisputed Truth.

On July 24, 2013, Brother Ali appeared on the Maximum Fun podcast Judge John Hodgman as an "Expert Witness".

[6] On April 4, 2017, he appeared on The Combat Jack Show: "The Brother Ali Episode" and on October 19, 2017, on BuzzFeed's See Something Say Something podcast.

Ali often makes fun of the media's constant urge to mention his albinism in the first lines of their reviews or newspaper articles.

[7] In an article titled "The Art of Mourning in America", Brother Ali said his favorite food is sweet potato pie.

During this time, Ali was selected to join a group of students on a Malaysian study tour, in which they explored ways that a more liberal Islamic society could peacefully coexist with different religions.

Much attention was garnered through Ali's album The Undisputed Truth, as it heavily criticized much about the United States' political system.

After the music video for "Uncle Sam Goddamn" was released in 2007, it quickly gained much attention, and shortly after, the United States Department of Homeland Security froze a money transfer to his record label.

While performing at a concert in 2015, Brother Ali endorsed Bernie Sanders for president of the United States, as a candidate in the upcoming 2016 presidential election.

In November 2019, Brother Ali performed at a Bernie Sanders rally in Minneapolis, Minnesota, alongside Representative Ilhan Omar.