Due to abundance and distribution throughout its biological range, this species could be used to investigate anthropogenic impacts on aquatic ecosystems by studying their movements.

[4] N. taxispilota is found in lower coastal regions from southeastern Virginia, through North Carolina, South Carolina, and Georgia, to northern and western Florida (Gulf Coast), then west through Missouri, Alabama, and Mississippi, to Louisiana, normally from sea level to 500 ft. (150 m) elevation.

[5] Dorsal scales are in 27–33 rows (more than any other North American water snake), and it has two to four anterior temporals (usually one in others).

N. taxispilota are widely distributed in the coastal and piedmont regions of the Southeastern United States.

Spatial Ecology and Movements of the Brown Water Snake (Nerodia taxispilota).