[1][2] Mau is the chief executive officer of Massive Change Network, a Chicago-based design consultancy he co-founded with his wife, Bisi Williams.

In 2003, while still at BMD, he founded the Institute Without Boundaries in collaboration with the School of Design at George Brown College, Toronto.

[7] In 2010, Mau left the company and went on to co-found Massive Change Network in Chicago with his wife, Bisi Williams.

[11] Mau stayed at Fifty Fingers for two years, before crossing the ocean for a brief sojourn at Pentagram in the UK.

Zone 1/2: The Contemporary City, a complex compendium of critical thinking about urbanism from philosophers such as Gilles Deleuze and Paul Virilio, architects Rem Koolhaas and Christopher Alexander remains one of his most notable works.

[citation needed] He is a member of the Royal Canadian Academy of Arts and served on the Herman Miller Design Council[15] from 2008 to 2012.

[17][18] In the 2010s, Bruce Mau Design was involved in the redevelopment and redesign of Ontario's ONroute service centres.

[19] As of November 19, 2015, Bruce Mau is the Chief Design Officer for Freeman, a brand experience company and service contractor.

[20] In September 2022, Bruce Mau and Bisi Williams undertook a collaboration with the University of New South Wales through the Massive Change Network (MCN).