[3] This order was later annulled, and the organization of Brule County governing structure was completed in September 1879.

The Missouri River flows southward along the western boundary line of Brule County.

For the first century of South Dakota statehood, the predominately white voters of Brule County favored the Democratic Party.

Since the "Reagan Revolution", voters in Brule County have shifted to favor Republican presidential candidates.

Michael Dukakis in 1988 was the last Democrat to win a majority in Brule County, although Bill Clinton twice obtained a plurality.

Four of the past five Republican nominees have won over 58 percent of Brule County's vote.

Media related to Brule County, South Dakota at Wikimedia Commons