Brush Creek is an unincorporated community in southern Laclede County, in the U.S. state of Missouri.
[2] A post office called Brush Creek was established in 1863, and remained in operation until 1975.
[3] The community takes its name from nearby Brush Creek.
[4] Brush Creek was designated a natural area on November 16, 1984.
This Laclede County, Missouri state location article is a stub.