It operates to over 100 destinations in Europe, North America and Africa and also offers charter services, maintenance and crew training.

On 12 April 2005, SN Airholding, the company behind SNBA, signed an agreement with Richard Branson, giving it control over Virgin Express.

Brussels Airlines increased its frequency to Abidjan (up to 6 weekly) and added Accra, Cotonou, Ouagadougou, and Lomé as new destinations.

The contract with Sabena Technics for the A330 and Boeing 737 ended on 1 January 2011 and Brussels Airlines will then do the plane maintenance.

On 1 June 2012,[12] Brussels Airlines inaugurated the route to New York JFK, operating daily with an Airbus A330-300 fitted with the new interior.

[14] It has been announced that as of March 2017, a new service to Mumbai will commence with 5 flights per week operated by a new Airbus A330-200 arriving early 2017.

On 30 January 2014, Brussels Airlines added 9 seasonal destinations and returned to the Polish market after some years of absence.

[15] In April 2015, Brussels Airlines was praised by the White House for continuing its normal flying operation to Western African countries during the Ebola outbreak, allowing essential aid to be delivered.

[16][17] All other airline companies, except Royal Air Maroc, suspended their flights to Sierra Leone, Liberia and Guinea.

In February 2018, CEO Bernard Gustin and financial director Jan De Raeymaeker resigned after a meeting with the Lufthansa board over the airline's future.

In December 2019, it was announced that Dieter Vranckx would replace Christina Foerster as CEO of Brussels Airlines effective January 1, 2020.

[25] Additionally, Brussels Airlines cancelled its wet-lease contract with CityJet, leading to the termination of eight European destinations in the wake of the pandemic.

[26] At the end of June 2020, Brussels Airlines also announced that they were cancelling several of flights scheduled for operation in September and October 2020.

[30] The company is headquartered in the b.house (Building 26) in the General Aviation Zone on the grounds of Brussels Airport and in Diegem, Machelen, Flemish Brabant.

With improving financial performance, rising cash reserves and a desire to reduce costs more rapidly, Brussels Airlines accelerated its fleet replacement plan by ordering 12 aircraft in August 2011.

[citation needed] Starting 2016, Brussels Airlines began phasing out its Avro RJ100s and replaced them with the Airbus A320 family and wet-leased Sukhoi Superjets.

[71] However, Brussels Airlines announced in July 2018 it would terminate the Superjet wet-lease contracts earlier than planned.

[73] In mid-2021, Brussels Airlines announced that it will take delivery of three Airbus A320neo aircraft in 2023 to replace ageing A319-100's and aim to lower CO2 emissions amongst its fleet.

[74] Brussels Airlines launched a series of Belgian Icon special liveries on its Airbus A320 fleet, all representing things that are typically Belgian, including Rackham (a Tintin themed aircraft), Magritte (an ode to the famous surrealist artist René Magritte), Trident (the aircraft for the Belgium national football team) and Amare (Tomorrowland Festival theme).

It was designed for the increasing number of customers who flew Brussels Airlines regularly and did not receive significant benefits from traditional frequent flyer programmes.

Additionally, business class has new lie-flat seats with an improved AVOD IFE system with 15 inch screens, supplied by the IMS-Company and known as "RAVE".