The original Buffalo Bisons baseball club played in the National League between 1879 and 1885.

The Bisons played their games at Riverside Park (1879–1883) and Olympic Park (1884–1885) in Buffalo, New York.

The original IL Bisons would leave in 1971 to Winnipeg, Manitoba, Canada as the Winnipeg Whips, before eventually landing in Scranton, Pennsylvania (after an additional five moves), the franchise currently plays in Moosic, Pennsylvania as the Scranton/Wilkes-Barre RailRiders.

[1] The current Buffalo Bisons, founded in 1979, include the history of the NL Bisons; it is thus the only NL team from the 19th century that both still exists and no longer plays in Major League Baseball.

Brouthers, Galvin, O'Rourke, Radbourn, and White are members of the Baseball Hall of Fame.