The station building was constructed in the Spanish Colonial Revival and Mission Revival architecture styles in 1894, opening for service on October 10 of that year.

[4] 18th-century tiles from the Mission San Antonio de Padua at Jolon and the Mission Dolores Asistencia at San Mateo were used for the station roof.

[4][3] Burlingame has two side platforms serving the line's two tracks.

This required use of the hold-out rule, where only one train could be at the station at a time.

[5][6] Media related to Burlingame station at Wikimedia Commons