Mwiri is approximately 14.6 kilometres (9 mi) by road, north-east of Jinja, the second largest city in the Uganda.

The country's first Prime Minister, the late Milton Obote, attended Busoga College Mwiri.

[1] Between 1930 and 1933, the school temporarily relocated to Kings College Budo in Wakiso District because of the poor accommodations at Kamuli.

In 1967, a proposal was made to merge Busoga College with nearby Wanyange Girls School.

The following year, however, the Busoga College Old Boys Association rejected the proposal and the idea was abandoned.