The Butler-McCook Homestead is a historic house museum at 396 Main Street in Hartford, Connecticut.

The Butler-McCook Homestead is located south of downtown Hartford, on the east side of Main Street at the Pulaski Mall.

The house stands on about 2 acres (0.81 ha) of land, part of which has formal gardens created by landscape architect Jacob Weidenman, the principal designer of Hartford's Bushnell Park.

The house remained in the hands of Butler descendants for about two centuries, prior to its conversion to a museum.

The house reflects two centuries of ownership by one family, with furnishings and decorative items ranging from the Colonial through the Victorian eras.