[2] In 1954, at age 17, Isella joined the group Los Sin Nombre (The Nameless), next to Thomas "Tutu" Campos, Javier E. Pantaleon, Luis Gualter Menu, and Higa.

After that, without Isella, recorded others for: "Los seguidores" (Sangre fronteriza), "Canción de lejos" (Desde el corazón...), "Viento no más" (Cantando), "Paloma y laurel"[6](Hoy!!).

[2] With Los Fronterizos, in 1964, participated in the historic original recording of "Misa Criolla", by Ariel Ramírez, considered the supreme work of Argentine music.

Their sound again amazed me, and I grabbed a crush on them.Isella then adhere fervently to the tenets of Movement of the New Songbook, which had launched Tejada Gómez, Mercedes Sosa, Mendoza Matus and other artists in 1963.

[3] In 1969 composed the music for "Canción con todos" (Song with all), to which the poet Armando Tejada Gómez I added lyrics, a topic that has been designated by the UNESCO as Anthem from Latin America and translated into thirty languages.

Among the plays performed in those years highlights the album Juanito Laguna (1976), the child character of the painter Antonio Berni, with music and poetry of Ástor Piazzolla, Horacio Ferrer, Atahualpa Yupanqui, Gustavo Leguizamón, Manuel J. Castilla, Armando Tejada Gómez, Eduardo Falu, Jaime Dávalos and himself.

[3] He returned to Argentina on 29 October 1983, when he had been democratically elected President Raúl Alfonsín, at which time it provided a pointed recital at the Estadio Obras Sanitarias.

At the time of return from exile, Isella participated in historical performances, as he did in the Luna Park with Horacio Guarany, the Cosquín Festival in the summer of 1984 and Sanitation mass readings of Silvio Rodríguez and Pablo Milanés, singers censored by the military regime.

[3] In 1984 he made with Victor Heredia and Quartet Zupay the show "Song for poetry", poems set to music composed by Pablo Neruda, Maria Elena Walsh and José Pedroni presented with a resounding success in the Luna Park, recital which later was released on an album that sold 300,000 copies.