The company was sold to the Córdoba Central Railway (CC) in 1912.

The C&R was founded in 1889 to acquire a concession, granted to William Temple in 1886 by the province of Santa Fe, for the construction of a line, 222 km long, from the river port of Rosario to San Francisco which would provide a link with the CC which had completed the building of a line from Córdoba to San Francisco the previous year.

Once the CC had completed the construction of a line from Buenos Aires to Rosario in 1912 through trains could reach Tucumán from the capital for the first time.

Close collaboration between the two companies led finally to the purchase of the Córdoba & Rosario by the CC in 1913.

Finally the Córdoba Central would be added to Ferrocarril Belgrano network after all the Argentine railways were nationalised in 1948.