Özdemir is the anchorman of the leading local and foreign affairs program 5N1K, broadcast on CNN Türk Television for 20 years now.

In 1996, Özdemir became an international war correspondent where he has reported on major political crisis sites at many of the world's hotspots including the Lebanese-Israeli border, Iraq and Afghanistan.

[1] In 1999, he helped found CNN Türk and in 2000, he began producing 5N1K,[Notes 1] an international news program.

Over the years, Özdemir has reported on major crises from many of world's hotspots including Iraq,[2] Afghanistan, Pakistan, the Palestinian territories and Israel.

In 2006, he visited the Guantánamo Bay detention camp in Cuba and produced an investigative news story there.

He made live broadcasts on YouTube -in front of the court- everyday and reported last updates about the case.

The world followed what's happening in Venezuela via Cüneyt Özdemir's exclusive news both from his YouTube channel and 5N1K program.

His other prominent works include interviews with Recep Tayyip Erdoğan, Christiane Amanpour, Noam Chomsky, Felice Casson Gladio, Orhan Pamuk, Zaha Hadid, Liz Hurley and Hugh Jackman.

He has written extensively on political affairs, global issues, pop-cultural developments, Middle East and Europe at this column.

His company also produces corporate promotion shootings, advertisements, viral videos both for internet and TV platforms as well as social media campaigns.

Over the years Özdemir's production company has worked with numerous important clients including Akbank, Kalebodur, Turkcell, Vodafone, Google, Ericson, Coca-Cola, Efes Pilsen, Tuborg, Unilever, Chevrolet and so on.

The company conducted this project with its partner Happy Idea and its participants TÜSEV (Turkish third sector trust) and Turk Journal.

"We Have a Message" project aimed at ameliorating communities' perception and understanding of each other and also at increasing the participation of their citizens.

The project also intended to emphasize the effects of European Union endorsements on social development with 8 short films and a documentary.

[7] Besides his career as an anchor on CacaTV (Kanal D & CNN Türk), he is one of the pioneers of digital media in Turkey.

In 2017, the world followed Reza Zarrab case from his YouTube exclusive live broadcasts daily.