In the 16th-18th centuries, intensive agriculture and wine-making industries developed and population grew as a consequence.

In 1761, in Căuşeni city, the Assumption Church was built with beautiful painted frescoes on the inside walls.

In 1991 as a result of the proclamation of the Independence of Moldova, part of Căușeni District joined with Tighina County (1991–2003).

Forests of the district are composed of tree species such as oak, ash, hornbeam, linden, maple, walnut and others.

The different types of manufacturing that predominate are: wine-making, processing of milk, bakery products, and other industries based on local raw materials.

The Party of Communists of the Republic of Moldova (PCRM) has seen a continuous fall in the percentage of the vote during the last three elections.

In the Căușeni District there are: 37 houses of culture, several folk bands with a Title 31 model, and 74 amateur artistic groups with a total of 1200 participants.

There is a School of Arts in Căușeni city, a school of Music in both Căinari and Copanca, a museum of history and ethnography of Căușeni, the "Alexei Mateevici House Museum" in Zaim, and in Cainari, a Museum of history and ethnography in Copanca, and 45 public Libraries including 9 branches for children].