[2] Prime Minister Phan Văn Khải launched construction of the bridge on September 25, 2004, which was scheduled to be completed in late 2008.

The bridge replaced the network of ferries on the National Route 1 linking Vĩnh Long Province on the east shore with Cần Thơ city on the westbank.

[4] A 90-meter approach ramp of the Cần Thơ Bridge collapsed during construction, on the morning of September 26, 2007, falling from 30 meters in the air.

[5] The collapsed section was above a small island located on the Vĩnh Long side of the bridge.

[6] There were 250 engineers and workers working on and under the span at the time;[7] the official death toll is 54, with 80 severe injuries.