The club's home stadium is the Estadio Bicentenario Calvo y Bascuñán, which has a capacity of 21,178.

On June 30, 1983 D. Antofagasta, coached by Manuel Rodríguez, returned to the top level once after defeating Lota Schwager 9–0.

D. Antofagasta experienced one of their most successful spans from 1991 through 1995, playing in the top tier under the guidance of Croatian coach Andrija Perčić, with star players such as Marco Cornez and Gabriel Caballero.

Current squad of Deportes Antofagasta as of 4 July 2022 (edit) Sources: ANFP Official Web Site Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.