Originally anchored by Jing Magsaysay, it premiered on March 16, 2015, as a standalone noontime newscast and was expanded into different editions since February 15, 2016.
The 15-minute weekend morning show Newsroom Junior Edition anchored by young contributors trained by CNN Philippines, from September 1, 2018 to March 15, 2020.
Ruth Cabal, Mai Rodriguez, Menchu Macapagal and David Santos serve as the final anchors.
It was first anchored by former CNN Philippines First Vice President for News and Public Affairs Jing Magsaysay and journalist Mai Rodriguez, who was held over from Newsday.
In September 2015, Magsaysay left the newscast after his resignation following the "right-sizing" retrenchment of 70 junior staffers and contractual employees, who worked in the company for Programming and Technical Engineering divisions, leaving Rodriguez as the sole anchor for the rest of its run.
On February 27, 2017, due to personnel reshuffling, Claire Celdran replaced Veloso at the 8 am slot while Network News anchor Pia Hontiveros took over the Global Newsroom chair.
Prior to a permanent weekend expansion, Rodriguez anchored special newscasts during severe weather coverage and other news of utmost importance.
Global Newsroom aired its last broadcast on December 29, 2017, to give way to the extension of Amanpour on January 1, 2018, as part of the network reorganization.
Mai Rodriguez was tapped to replace Mercado while selected correspondents are doing the weekend edition for the month of June and July.
However, when special events warrant during the early primetime slot, this function goes to News Night with Pia Hontiveros until 8:00 pm and only under the direst situations would warrant preemption of the weeknight 9:00 pm edition in favor of uninterrupted coverage starting from where News Night leaves off.
Mico Halili co-anchored the broadcast with Claire Celdran and Dr. Freddie Gomez providing medical perspective, augmenting the network's extended bulletins done on the day of Ali's death.
At Battle of Marawi on May 23, 2017, the entire primetime current affairs block gave way to initial developments of the unfolding situation in the city with Pia Hontiveros anchoring uninterrupted coverage for four hours from 6:00 to 10:00 pm.
The coverage was heavily delivered in Filipino on the first two blocks before reverting to English on the extended slot of Global Newsroom.
On March 30, 2020, the network brought back a special edition of Newsroom on its 9 pm timeslot with Rico Hizon as an anchor.