Founded in 1960, it currently competes in Liga IV – Mehedinți County, the fourth tier of Romanian football.

The club was established in the early 1960s and before 1990 won four county championships, finally earning promotion to Liga III at the end of the 1985–86 season.

Building Vânju Mare was owned by Mihaela Giuca, the first woman to be in charge of a football club in Romania.

[1][2][3] Mihaela Giuca's team played its home matches on the Municipal Stadium in Drobeta-Turnu Severin in the first two seasons of Divizia B.

After another three years, Building moved to Orșova, following a conflict with the Commune of Vânju Mare, which allowed Minerul Mehedinți to play its home matches on the same ground.