CYP105 family

Cytochrome P450, family 105, also known as CYP105, is a cytochrome P450 monooxygenase family in bacteria, predominantly found in the phylum Actinomycetota and the order Actinomycetales.

[2][3] The first three genes and subfamilies identified in this family is the herbicide-inducible P-450SU1 (CYP105A1, subfamily A) and P-450SU2 (CYP105B1, subfamily B) from Streptomyces griseolus[4][5] and choP (CYP105C1, subfamily C) from Streptomyces sp's cholesterol oxidase promoter region.

CYP105 enzymes is widely used in industry, such as the production of pravastatin.

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The evolutionary divergence of the CYP superfamily collected in 1990, CYP105A, B and C is in the branch of prokaryotic CYPs [ 1 ]