Cabaiguán (Spanish pronunciation: [kaβajˈɣwan]) is a municipality and town in the province of Sancti Spíritus, Cuba.

The municipality is divided into the consejos populares (i.e. "popular councils") of Cabaiguán and the villages of Neiva, Pedro Barba, Guayos and Santa Lucía.

Cabaiguan was known as the Cuban epicenter of migration from the Canary Islands.

It also has an oil refinery built in 1947 and the Nieves Morejon quarry, where the Provincial Prison is located.

The town straddles the Carretera Central highway and is served by the A1 motorway.