In mid-September, 2012, Marvel Comics announced that a new title Cable and X-Force would be published in December, headed by the creative team of Dennis Hopeless and Salvador Larroca.
It features a team of Cable, Psylocke, Fantomex and Marrow, written by X-Men: Legacy writer Simon Spurrier.
After being reunited with one another, Cable and Hope both share a vision in which a tanker hits the shore in Miami Beach and from which a mysterious mass comes out.
Some days earlier, Domino saves people from the mysterious mass in Miami Beach by teaming up with Hope.
He later finds out that Teresa lost her daughter during Xorn's attack on New York which is why she has been so vocal against mutant's rights; however, she is not the one who created the virus.
Nemesis then go straight to the Eat-More facility in order to destroy the virus but find Colossus fighting Girth mutants when they arrive.
Doctor Nemesis, who had been trying to find a cure to the virus the entire time, realizes that his attempts have backfired because the victims only became even more dangerous.
The authorities, including Havok and his Uncanny Avengers, only arrived after all the workers’ mutated bodies morphed back to their regular human forms and were strewn dead across the floor.
After destroying the headquarters and using the teleportation gate to run away from Havok and his team, X-Force decides to split up and reunite later on.
Nemesis and Forge hide out in a junk yard and find new challenges to pass the time, like arcade games and battling giant robots.
Colossus is able to launch himself into the alien ship and free the team, but they them maroon Brand since they won't turn themselves in.
It turns out she visited Pace Federal Penitentiary and stole the powers of Purple Woman and Lady Mastermind, which she uses to create a diversion in order to escape and track down her father.
X-Force is split into two teams, with Hope and Cable battling The Reavers and Domino and Colossus breaking into a Trask base guarded by a sentinel.
Then Hope views one of Cable's premonitions and sneaks out of the bunker in search of Bishop, who is now part of the Uncanny X-Force.
She is not aware that Bishop has traveled back into the future in penance for terrorizing Cable and Hope while she grew up in a parallel time line.
Stryfe attempts to prove to Cable that he did a poor job of raising Hope by manipulating her into killing Bishop.
Nemesis and Forge create a Cerebro out of junkyard parts and use Psylocke's telepathy to track down Spiral and Stryfe's base.
Stryfe thinks he's won when Hope stabs Bishop, but she carefully strikes to miss all vital organs.