Cabramatta station opened in 1870 on the Granville to Liverpool section of the Main South line.

[4] The station received lifts as part of an easy access upgrade in 2004.

[5][page needed] As part of the Southern Sydney Freight Line project, a third line was built behind the eastern side of the station.

Due to limited space, an overhead concourse was constructed to replace a building on platform 2.

[6][7][8] Transdev NSW operates one bus route via Cabramatta station, under contract to Transport for NSW: Transit Systems operates five bus routes via Cabramatta station, under contract to Transport for NSW: Cabramatta station is served by one NightRide route: