Caddo Gap is an unincorporated community and census-designated place (CDP) in Montgomery County, Arkansas, United States.

[3] It is best known as the area in which explorer Hernando de Soto and his forces clashed with the Native American Tula tribe in 1541, a band loosely affiliated with the Caddo Confederacy.

The expedition described the Tula Indians as the fiercest they had faced during their inward journey into North America.

[4] After this, the expedition turned back east, making it as far as the Mississippi River, where de Soto died.

[4] During the night of June 10–11, 2010, a flash flood along Little Missouri River killed at least 20 people in the campgrounds of the Albert Pike Recreation Area near Caddo Gap.