The Cadillac Cien has a longitudinally mounted 60-degree, 7.5-liter V12 that produced 750 hp (559 kW) and 650 lb⋅ft (881 N⋅m) of torque.

The Cien was designed at General Motors' Advanced Design Studio in England and built as a fully working road-going vehicle with the help of the UK-based engineering and motorsport company Prodrive.

The Cien's monocoque chassis and body are made of aerogel composite and equipped with active aero.

[4] Initially, there were plans to put it into production, but due to the lack of development funds and the high expected selling price of US$200,000, the existence of a customer base for the Cien was put into question.

The Cadillac Cien is a playable vehicle in video games including Gran Turismo, Midnight Club 3: DUB Edition Remix, and Asphalt 9: Legends.