In 1914, following the completion of his studies in Paris, he returned to Russia and enrolled at the Saint Petersburg State University, where he again met Çelebicihan.

In September 1917, together with Amet Özenbaşlı, he was part of a Crimean Tatar delegation to the Congress of the Enslaved Peoples of Russia.

According to the memoirs of Pyotr Wrangel, he was offered control over the nascent Crimean military forces by Seydamet, but refused the offer: Following the example of the Don and Ukraine, in the face of the impending red wave, the Crimean Tatars also decided to organize themselves in the figure of a Kurultay [...] Democratic politics prevailed, the prime representative of which was the Prime Minister and Minister of War Seydamet, following the example of Mr. Kerensky, also from lawyers.

During his time as Minister of Foreign Affairs, Seydamet was involved in attempts to negotiate a deal with Pavlo Skoropadskyi for recognition of the Crimean Regional Government's independence.

Seydamet's return to Istanbul drew attention, as the city was then under occupation by the Western Allies, and Turkey was in the midst of a war against Greece.

At a meeting of the Prometheanist movement in January 1930 in Warsaw, he drew comparisons between the Soviet Union and the Russian Empire, accusing them of using the same tactics in attempting to harm the Crimean Tatar people.

In 1941, Seydamet, in addition to Mustafa Szynkiewicz and Müstecib Ülküsal [ru], travelled to Nazi Germany in an unsuccessful attempt to achieve German support in establishing an independent Crimean Tatar state.

In spite of these attempts, Seydamet remained opposed to Nazism, and maintained close ties to the Polish government-in-exile in London.