Situated in Sector 1, and having a length of 2.7 kilometres (1.7 mi), it leads from Splaiul Independenței [ro] (which runs parallel to the Dâmbovița River) to the north and then northwest up to Piața Victoriei, where Șoseaua Kiseleff continues north.

[5] Podul Mogoșoaiei was the first street in Bucharest to be illuminated with candles during the night, starting July 1814.

The road was renamed "Calea Victoriei" on October 12, 1878, following the Romanian victory in the Independence War of 1877–1878.

As of 2023 the association streets for people (in Romanian: Străzi Pentru Oameni) started a petition to make the entire avenue fully pedestrian.

Major buildings and monuments along the street include (from north to south): The avenue was also long home to the Constantin Tănase Revue Theatre (as of 2006, relocated to the Lipscani district), and was the site of the old Romanian National Theater, just north of Palatul Telefoanelor; the departed theatre's façade is replicated by the front of the Bucharest Novotel that opened in summer 2006.