Calgary-Klein is a provincial electoral district in Calgary, Alberta, Canada.

The district was created in the 2010 boundary redistribution and is mandated to return a single member to the Legislative Assembly of Alberta using the first past the post voting system.

The electoral district was created in the 2010 Alberta boundary re-distribution.

Prior to the election of New Democrat candidate Craig Coolahan in 2015, the antecedent electoral districts that comprise Calgary-Klein elected Progressive Conservative candidates since the 1970s.

The seat returned to the NDP in the 2023 Alberta general election.