Calhoun is a city in Henry County, Missouri, United States.

[4] The town was named after John C. Calhoun, seventh Vice President of the United States.

There were 208 housing units at an average density of 212.2 per square mile (81.9/km2).

29.7% of all households were made up of individuals, and 9.2% had someone living alone who was 65 years of age or older.

The racial makeup of the city was 97.35% White, 0.81% Native American, 1.02% Pacific Islander, and 0.81% from two or more races.

31.2% of all households were made up of individuals, and 20.6% had someone living alone who was 65 years of age or older.